Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10400005 | 0.87 | BACE1 (0.35) | BACE1ARALOX5APFEN1TRPA1 | |
| SCHEMBL2313436 | 0.81 | AR (0.49) | BACE1ARALOX5APFEN1TRPA1 | |
| SCHEMBL11900334 | 0.79 | BACE1 (0.56) | BACE1ARALOX5APFEN1TRPA1 | |
| SCHEMBL29655141 | 0.79 | BACE1 (0.56) | BACE1ARALOX5APFEN1TRPA1 | |
| SCHEMBL29805892 | 0.78 | BACE1 (0.51) | BACE1ARALOX5APFEN1TRPA1 | |
| SCHEMBL29065978 | 0.78 | BACE1 (0.51) | BACE1ARALOX5APFEN1TRPA1 | |
| SCHEMBL2311209 | 0.77 | TRPA1 (0.51) | BACE1ARALOX5APFEN1TRPA1 | |
| SCHEMBL10398384 | 0.75 | TRPA1 (0.39) | BACE1ALOX5APFEN1TRPA1TRPM8 | |
| SCHEMBL22304414 | 0.72 | AR (0.58) | BACE1ARALOX5APFEN1TRPA1 | |
| SCHEMBL23934168 | 0.72 | AR (0.50) | BACE1ARTRPA1SCN9ATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4931487-A | Chain extenders for polyurethanes | DOW CHEMICAL COMPANY | 1990-06-05 | — | — | US | disclosed |