Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5013719 | 0.86 | CYP2C9 (0.59) | CYP2C9CYP2C19TP53CYP2D6ALOX15 | |
| SCHEMBL12339835 | 0.77 | TP53 (0.44) | CYP2C9CYP2C19TP53CYP2D6ALOX15 | |
| SCHEMBL225240 | 0.77 | CYP2C19 (0.55) | CYP2C9CYP2C19TP53CYP2D6ALOX15 | |
| SCHEMBL30241127 | 0.77 | CYP2C19 (0.55) | CYP2C9CYP2C19TP53CYP2D6ALOX15 | |
| SCHEMBL1070452 | 0.75 | TP53 (0.50) | CYP2C9CYP2C19TP53CYP2D6ALOX15 | |
| SCHEMBL30623136 | 0.75 | TP53 (0.50) | CYP2C9CYP2C19TP53CYP2D6ALOX15 | |
| SCHEMBL2017741 | 0.75 | CYP2C9 (0.62) | CYP2C9CYP2C19TP53CYP2D6ALOX15 | |
| SCHEMBL2017743 | 0.75 | CYP2C9 (0.62) | CYP2C9CYP2C19TP53CYP2D6ALOX15 | |
| SCHEMBL1069000 | 0.72 | ALOX15 (0.67) | CYP2C9CYP2C19TP53CYP2D6ALOX15 | |
| SCHEMBL31206030 | 0.72 | ALOX15 (0.67) | CYP2C9CYP2C19TP53CYP2D6ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4927930-A | LIGHT, HEAT AND OXIDATION STABILIZERS FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1990-05-22 | — | — | US | disclosed |