Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.44 |
| ▸ | FEN1 | P39748 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 2/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | HEXA | P06865 | 1/20 | 0.41 |
| ▸ | HEXB | P07686 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11367319 | 0.82 | ADORA2A (0.46) | ADORA2AALOX5APFEN1DPP4LCK | |
| SCHEMBL17204254 | 0.75 | PIK3CG (0.54) | ALOX5APFEN1PRKDCATRPIK3CD | |
| SCHEMBL3425059 | 0.73 | ADORA2A (0.56) | ADORA2ADPP4LCKKDRJAK3 | |
| SCHEMBL28174453 | 0.73 | ATR (0.56) | ADORA2AALOX5APFEN1LCKKDR | |
| SCHEMBL19968759 | 0.71 | BACE1 (0.47) | ADORA2ADPP4HEXAHEXBCTSD | |
| SCHEMBL29464888 | 0.71 | BACE1 (0.47) | ADORA2ADPP4HEXAHEXBCTSD | |
| SCHEMBL28107573 | 0.70 | FEN1 (0.66) | ALOX5APFEN1 | |
| SCHEMBL17203726 | 0.70 | PIK3CA (0.54) | PRKDCATRPIK3CDPIK3CAPIK3CG | |
| SCHEMBL4464780 | 0.69 | FGFR1 (0.55) | ADORA2ALCKKDRJAK3MAPK14 | |
| SCHEMBL19981533 | 0.69 | LIMK1 (0.55) | ADORA2AALOX5APFEN1LCKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4931487-A | Chain extenders for polyurethanes | DOW CHEMICAL COMPANY | 1990-06-05 | — | — | US | disclosed |