Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8966053 | 0.89 | TSHR (0.64) | TSHRTHRBALDH1A1 | |
| SCHEMBL11304474 | 0.85 | TSHR (0.60) | TSHRTHRBALDH1A1 | |
| SCHEMBL4268354 | 0.85 | TSHR (0.59) | TSHRTHRBALDH1A1TGFBR1 | |
| SCHEMBL346926 | 0.85 | TSHR (0.59) | TSHRTHRBALDH1A1TGFBR1 | |
| SCHEMBL5827538 | 0.85 | TSHR (0.59) | TSHRTHRBALDH1A1TGFBR1 | |
| SCHEMBL2585229 | 0.84 | TSHR (0.68) | TSHRTHRBALDH1A1 | |
| SCHEMBL20854815 | 0.84 | TSHR (0.68) | TSHRTHRBALDH1A1 | |
| SCHEMBL1372597 | 0.82 | TSHR (0.67) | TSHRTHRBALDH1A1 | |
| SCHEMBL306496 | 0.81 | TSHR (0.55) | TSHRTHRBALDH1A1TGFBR1 | |
| SCHEMBL306870 | 0.81 | TSHR (0.55) | TSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921930-A | ABRASION RESISTANT POLYESTERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-05-01 | — | — | US | claimed |
| US-4910281-A | Polyurethane from diol and diisocyanate | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-03-20 | — | — | US | claimed |
| US-4921930-A | ABRASION RESISTANT POLYESTERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-05-01 | — | — | US | disclosed |
| US-4910281-A | Polyurethane from diol and diisocyanate | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-03-20 | — | — | US | disclosed |
| EP-0309249-A2 | Acryloyloxy and methacryloyloxy group-containing condensation polymers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-03-29 | — | — | EP | disclosed |