SCHEMBL2585229

SCHEMBL2585229

C=C(C)C(=O)OCC(O)C(O)COC(=O)C(=C)C

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.68
THRB P10828 1/20 0.47
ALDH1A1 P00352 4/20 0.44
TDP1 Q9NUW8 2/20 0.34
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
CASP1 P29466 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20854815 1.00 TSHR (0.68) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL13668621 0.92 TSHR (0.59) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL5827538 0.92 TSHR (0.59) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL4268354 0.92 TSHR (0.59) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL346926 0.92 TSHR (0.59) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL2845172 0.91 TSHR (0.63) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL3503123 0.91 TSHR (0.63) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL2845656 0.91 TSHR (0.63) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL1372597 0.89 TSHR (0.67) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL2981728 0.87 TSHR (0.64) TSHRTHRBALDH1A1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050042363-A1 Method for fabrication of biochips with a macroporous polymer substrate U CHICAGO ARGONNE LLC 2005-02-24 US claimed
CN-115109185-B Inkjet active energy ray-curable composition, three-dimensional object manufacturing method, and three-dimensional object manufacturing apparatus 株式会社理光 2024-08-23 CN disclosed
US-11905425-B2 Inkjet active-energy-ray-curable composition, three-dimensional object producing method, and three-dimensional object producing apparatus RICOH COMPANY, LTD. (JP) 2024-02-20 US disclosed
US-20220306880-A1 INKJET ACTIVE-ENERGY-RAY-CURABLE COMPOSITION, THREE-DIMENSIONAL OBJECT PRODUCING METHOD, AND THREE-DIMENSIONAL OBJECT PRODUCING APPARATUS RICOH COMPANY, LTD. (JP) 2022-09-29 US disclosed
EP-4063461-A1 INKJET ACTIVE-ENERGY-RAY-CURABLE COMPOSITION, THREE-DIMENSIONAL OBJECT PRODUCING METHOD, AND THREE-DIMENSIONAL OBJECT PRODUCING APPARATUS Ricoh Company, Ltd. (JP) 2022-09-28 EP disclosed
CN-115109185-A Inkjet active energy ray-curable composition, three-dimensional object manufacturing method, and three-dimensional object manufacturing apparatus 株式会社理光 2022-09-27 CN disclosed
US-10781166-B2 Biocompositions for 3D printing 3D-BIOMATERIALS, LLC (US) 2020-09-22 US disclosed
EP-3687976-A1 BIOCOMPOSITIONS FOR 3D PRINTING 3D - Biomaterials, LLC (US) 2020-08-05 EP disclosed
US-10590066-B2 Biocompositions for 3D printing 3D-BIOMATERIALS, LLC (US) 2020-03-17 US disclosed
US-20190194123-A1 BIOCOMPOSITIONS FOR 3D PRINTING 3D - BIOMATERIALS, LLC 2019-06-27 US disclosed
EP-1365915-A1 POLYMER GEL CONTACT MASKS AND METHODS AND MOLDS FOR MAKING SAME Surface Logix, Inc. (US) 2003-12-03 EP disclosed
WO-2003039713-A1 ANTI-PATHOGENIC AIR FILTRATION MEDIA AND AIR HANDLING DEVICES HAVING PROTECTIVE CAPABILITIES AGAINST INFECTIOUS AIRBORNE MICROORGANISMS INNOVATIVE CONSTRUCTION AND BUILDING MATERIALS, LLC (US) 2003-05-15 WO disclosed
WO-2002036342-A1 POLYMER GEL CONTACT MASKS AND METHODS AND MOLDS FOR MAKING SAME SURFACE LOGIX, INC. (US) 2002-05-10 WO disclosed
US-5547762-A THERMOSETTING RESIN LAYER BRIDGESTONE CORPORATION (JP) 1996-08-20 US disclosed
EP-0320023-B1 Macroporous polymeric membranes, their preparation and their use for polymer separation CESKOSLOVENSKA AKADEMIE VED (CS) 1994-09-21 EP disclosed
US-4952349-A Macroporous polymeric membranes for the separation of polymers and a method of their application CESKOSLOVENSKA AKADEMIE VED (CS) 1990-08-28 US disclosed
US-4923610-A COPOLYMER OF (METH)ACRYLATE, VINYLPYRIDINE, N-VINYLPYRROLIDONE, VINYL ACETATE OR HYDROXYSTYRENE WITH DIVINYL MONOMER; GLOBULES; ELUTION, DETECTION, COLLECTION Ceskoslovenska akademive ved and Akademia Nauk SSSR (CS) 1990-05-08 US disclosed
US-4889632-A CROSSLINKED GLOBULES OF ADDITION POLYMERS CONNECTED BY COVALENT BONDS TO FORM VOIDS; FOR BIOPOLMERS, SUCH AS PROTEINS, ENZYMES, POLYPEPTIDES CESKOSLOVENSKA AKADEMIE VED (CS) 1989-12-26 US disclosed
EP-0320023-A2 Macroporous polymeric membranes, their preparation and their use for polymer separation Ceskoslovenska akademie ved (CS) 1989-06-14 EP disclosed
US-4340483-A Polar polymeric sorbent based on glycidyl esters for gas and liquid chromatography CESKOSLOVENSKA AKADEMIE VED (CS) 1982-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190194123-A1 BIOCOMPOSITIONS FOR 3D PRINTING HTR3D, ILK, ITGB3 TSHR 4733/4885THRB 4743/4885ALDH1A1 1925/4885
US-10590066-B2 Biocompositions for 3D printing HTR3D, ILK, ITGB3 TSHR 4733/4885THRB 4743/4885ALDH1A1 1925/4885
US-10781166-B2 Biocompositions for 3D printing HTR3D, ILK, ITGB3 TSHR 4733/4885THRB 4743/4885ALDH1A1 1925/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.