⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16162588 | 0.96 | — | — | |
| SCHEMBL23419577 | 0.82 | — | — | |
| Acetamidine SCHEMBL30712355 | 0.78 | — | — | |
| Acetamide SCHEMBL27859287 | 0.78 | — | — | |
| Acetone SCHEMBL1277371 | 0.78 | — | — | |
| Acetamidine SCHEMBL395042 | 0.75 | — | — | |
| Acetic Acid SCHEMBL28886845 | 0.75 | FFAR3 (0.58) | — | |
| SCHEMBL288532 | 0.75 | — | — | |
| Acetic Acid SCHEMBL28694434 | 0.75 | FFAR3 (0.58) | — | |
| SCHEMBL29222480 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021042171-A1 | CANCER IMMUNOTHERAPY | Ena Therapeutics Pty Ltd (AU) | 2021-03-11 | — | — | WO | disclosed |
| WO-2017189868-A1 | SERINE REPLACEMENT POLYMYXIN ANALOGUES USEFUL AS ANTIBIOTIC POTENTIATORS | SPERO OPCO (US) | 2017-11-02 | — | — | WO | disclosed |
| EP-2925721-B1 | S1P AND/OR ATX MODULATING AGENTS | BIOGEN MA INC (US) | 2017-06-07 | — | — | EP | disclosed |
| CN-103998063-B | Polyethylene glycol based prodrugs of adrenomedullin and uses thereof | 拜耳制药股份公司 | 2016-09-21 | — | — | CN | disclosed |
| CN-103987407-B | Pyrrolobenzodiazepines Zhuo and conjugate thereof | 麦迪穆有限责任公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-102123723-B | Glucagon/GLP-1 receptor co-agonists | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORP. (US) | 2016-05-25 | — | — | CN | disclosed |
| EP-2276732-B1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KAROBIO AB (SE) | 2015-05-20 | — | — | EP | disclosed |
| CN-102459325-B | Gastrostatin receptor activated glucagon compounds | UNIV INDIANA RES & TECH CORP | 2015-03-25 | — | — | CN | disclosed |
| CN-102933236-B | Pyrrolobenzodiazepines and conjugates thereof | SPIROGEN LTD. (CH) | 2014-10-08 | — | — | CN | disclosed |
| CN-103998063-A | Polyethylene glycol based prodrugs of adrenomedullin and uses thereof | Bayer Pharma AG | 2014-08-20 | — | — | CN | disclosed |
| CN-103987407-A | Pyrrolobenzodiazepines and conjugates thereof | SPIROGEN SARL | 2014-08-13 | — | — | CN | disclosed |
| US-8653072-B2 | Estrogen receptor ligands | KARO BIO AB (SE) | 2014-02-18 | — | — | US | disclosed |
| US-20130131061-A1 | Novel Estrogen Receptor Ligands | KARO BIO AB (SE) | 2013-05-23 | — | — | US | disclosed |
| CN-102933236-A | Pyrrolobenzodiazepines and conjugates thereof | SPIROGEN LTD | 2013-02-13 | — | — | CN | disclosed |
| US-8367665-B2 | Estrogen receptor ligands | KARO BIO AB (SE) | 2013-02-05 | — | — | US | disclosed |
| US-20110190294-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | OASMIA PHARMACEUTICAL AB (SE) | 2011-08-04 | — | — | US | disclosed |
| EP-2276732-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-01-26 | — | — | EP | disclosed |
| WO-2009127686-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2009-10-22 | — | — | WO | disclosed |
| CN-101208306-A | Pyrazole compounds and diabetes therapeutic agent containing the same | JAPAN TOBACCO INC (JP) | 2008-06-25 | — | — | CN | disclosed |
| CN-1265590-A | Substituted alkanohydroxamic acid and method of reducing TNF 'alpha' levels | CELGENE CORP (US) | 2000-09-06 | — | — | CN | disclosed |