Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28387209 | 0.91 | TSHR (0.62) | TSHRTHRBALDH1A1TDP1CYP3A4 | |
| SCHEMBL10400584 | 0.90 | TSHR (0.53) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL10399613 | 0.87 | TSHR (0.50) | TSHRTHRBALDH1A1TDP1CYP3A4 | |
| SCHEMBL6457085 | 0.86 | TSHR (0.56) | TSHRTHRBALDH1A1FAAH | |
| SCHEMBL29187279 | 0.86 | TSHR (0.56) | TSHRTHRBALDH1A1TDP1CYP3A4 | |
| SCHEMBL4526188 | 0.85 | TSHR (0.69) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL650461 | 0.85 | TSHR (0.59) | TSHRTHRBFAAH | |
| SCHEMBL652336 | 0.85 | TSHR (0.59) | TSHRTHRBFAAH | |
| SCHEMBL8204683 | 0.85 | TSHR (0.59) | TSHRTHRBFAAH | |
| SCHEMBL6748216 | 0.85 | TSHR (0.59) | TSHRTHRBFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935488-A | ALKYD RESINS, POLYESTERS, FILMS, COATINGS; PHOTOPOLYMERIZABLE UNSATURATED ESTERS; FAST CURING | Kurary Company, Ltd. (JP) | 1990-06-19 | — | — | US | claimed |
| EP-0338540-A2 | Trimethylolheptanes and use thereof | KURARAY CO., LTD. (JP) | 1989-10-25 | — | — | EP | claimed |