SCHEMBL1040037

SCHEMBL1040037

O=C(O)N1C=CSN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7057853 0.65
SCHEMBL3262997 0.54
SCHEMBL15201661 0.52
Bicarbonate SCHEMBL27897155 0.46
Bicarbonate SCHEMBL139033 0.46
Benzene SCHEMBL27907662 0.42 FFAR3 (0.70)
Benzene SCHEMBL5081287 0.42 CA1 (0.71)
Benzene SCHEMBL10964916 0.42 CA1 (0.71)
Benzene SCHEMBL10961254 0.42 CA1 (0.71)
SCHEMBL498690 0.42

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102718731-A 4 /5-methyl-1, 2, 3-thiadiazole formic acid derivative and preparation method thereof UNIV TIANJIN COMMERCE 2012-10-10 CN claimed
CN-1759095-A N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives ELAN PHARM INC (US) 2006-04-12 CN claimed
CN-1231480-C 1,2, 3-thiadiazole carboxylic acid (thio) esters and their use as pest control agents and microbicides BAYER AG (DE) 2005-12-14 CN claimed
EP-1453789-A2 N,N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES Elan Pharmaceuticals, Inc. (US) 2004-09-08 EP claimed
CN-1112849-C Use of 1,2, 3-thiadiazole carboxylic acid (thio) esters for controlling pests BAYER AG (DE) 2003-07-02 CN claimed
WO-2003040096-A2 N, N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES ELAN PHARMACEUTICALS, INC. (US) 2003-05-15 WO claimed
WO-2003033712-A1 CHEMICALLY INDUCIBLE PROMOTERS FROM BARLEY AND USE THEREOF BASF PLANT SCIENCE GMBH (DE) 2003-04-24 WO claimed
CN-1208324-A Use of 1,2, 3-thiadiazole carboxylic acid (thio) esters for controlling pests BAYER AG (DE) 1999-02-17 CN claimed
CN-1207739-A 1,2, 3-thiadiazole carboxylic acid (thio) esters and their use as pest control agents and microbicides BAYER AG (DE) 1999-02-10 CN claimed
WO-2025068514-A1 SUBSTITUTED HETEROCYCLIC CARBOXAMINDES AND USE THEREOF BAYER AKTIENGESELLSCHAFT (DE) 2025-04-03 WO disclosed
WO-2023067515-A1 THIADIAZOLYL COMPOUNDS AS DNA POLYMERASE THETA INHIBITORS IDEAYA BIOSCIENCES, INC. (US) 2023-04-27 WO disclosed
EP-3774782-A2 ATF6 INHIBITORS AND USES THEREOF Black Belt TX Ltd (GB) 2021-02-17 EP disclosed
EP-3414239-A2 INHIBITORS OF RECEPTOR-INTERACTING PROTEIN KINASE 1 Denali Therapeutics Inc. (US) 2018-12-19 EP disclosed
CN-108707124-A A kind of synthetic method of the final intermediate product of thiazole carboxylic acid's class chemical intermediate 河南福萌商贸有限公司 2018-10-26 CN disclosed
CN-1208324-A Use of 1,2, 3-thiadiazole carboxylic acid (thio) esters for controlling pests BAYER AG (DE) 1999-02-17 CN disclosed
CN-1207739-A 1,2, 3-thiadiazole carboxylic acid (thio) esters and their use as pest control agents and microbicides BAYER AG (DE) 1999-02-10 CN disclosed
CN-1180297-A Agricultural and horticultural disease control agent and method for controlling these diseases NIHON NOHYAKU CO LTD (JP) 1998-04-29 CN disclosed
CN-1134936-A Herbicidal (1,2,4) thiadiazoles AMERICAN CYANAMID CO (US) 1996-11-06 CN disclosed
EP-0672059-A1 CYCLIC COMPOUNDS LINKED BY A HETEROCYCLIC RING USEFUL AS INHIBITORS OF PLATELET GLYCOPROTEIN IIb/IIIa THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1995-09-20 EP disclosed
EP-0064582-B1 STARTING COMPOUNDS FOR PREPARING CEPHEM COMPOUNDS AND PROCESSES FOR THEIR PREPARATION FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1985-12-11 EP disclosed