⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4073685 | 0.69 | — | — | |
| Water SCHEMBL8221741 | 0.67 | — | — | |
| SCHEMBL1261690 | 0.65 | — | — | |
| SCHEMBL4294981 | 0.65 | — | — | |
| SCHEMBL15201661 | 0.56 | — | — | |
| Benzene SCHEMBL5081287 | 0.46 | CA1 (0.71) | — | |
| Benzene SCHEMBL10964916 | 0.46 | CA1 (0.71) | — | |
| Benzene SCHEMBL10961254 | 0.46 | CA1 (0.71) | — | |
| Benzene SCHEMBL377044 | 0.46 | CA1 (0.71) | — | |
| Benzene SCHEMBL1122633 | 0.46 | CA1 (0.71) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111269247-B | Preparation method of buprofezin drug molecule with escherichia coli inhibition effect | 河南科技大学第一附属医院 | 2020-11-24 | — | — | CN | claimed |
| EP-2471797-B1 | 17-DESMETHYLRAPAMYCIN AND ANALOGUES THEREOF, METHODS FOR THEIR PRODUCTION AND THEIR USE AS IMMUNOSUPRESSANTS, ANTICANCER AGENTS, ANTIFUNGAL AGENTS ETC. | BUCK INST FOR RES ON AGING (US) | 2016-02-03 | — | — | EP | disclosed |
| EP-2471797-A2 | 17-Desmethylrapamycin and analogues thereof, methods for their production and their use as immunosupressants, anticancer agents, antifungal agents etc. | Biotica Technology Limited (GB) | 2012-07-04 | — | — | EP | disclosed |
| US-7803808-B2 | Production of polyketides and other natural products | WYETH LLC (US) | 2010-09-28 | — | — | US | disclosed |
| US-20090253732-A1 | Production Of Polyketides And Other Natural Products | BIOTICA TECHNOLOGY LIMITED | 2009-10-08 | — | — | US | disclosed |
| EP-2029611-A2 | 17-DESMETHYLRAPAMYCIN AND ANALOGUES THEREOF, METHODS FOR THEIR PRODUCTION AND THEIR USE AS IMMUNOSUPRESSANTS, ANTICANCER AGENTS, ANTIFUNGAL AGENTS ETC. | Biotica Technology Limited (GB) | 2009-03-04 | — | — | EP | disclosed |
| CN-101217955-A | Bicyclic 6-alkylidene-penems as class D beta-lactamases inhibitors | WYETH CORP (US) | 2008-07-09 | — | — | CN | disclosed |
| US-7332354-B2 | Compounds for chemiluminescense procedures | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2008-02-19 | — | — | US | disclosed |
| WO-2006016167-A2 | 17-DESMETHYLRAPAMYCIN AND ANALOGUES THEREOF, METHODS FOR THEIR RODUCTION AND THEIR USE AS IMMUNOSUPRESSANTS, ANTICANCER AGENTS, ANTIFUNGAL AGENTS, ETC. | BIOTICA TECHNOLOGY LIMITED (GB) | 2006-02-16 | — | — | WO | disclosed |
| US-20040214999-A1 | Novel compounds for chemiluminescense procedures | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2004-10-28 | — | — | US | disclosed |
| EP-1397678-A1 | LUCIFERIN HYDRAZIDES | Roche Diagnostics GmbH (DE) | 2004-03-17 | — | — | EP | disclosed |
| EP-1397488-A1 | NOVEL COMPOUNDS FOR CHEMILUMINESCENSE PROCEDURES | Roche Diagnostics GmbH (DE) | 2004-03-17 | — | — | EP | disclosed |
| WO-2002099097-A1 | NOVEL COMPOUNDS FOR CHEMILUMINESCENSE PROCEDURES | ROCHE DIAGNOSTICS GMBH (DE) | 2002-12-12 | — | — | WO | disclosed |
| WO-2002099428-A1 | LUCIFERIN HYDRAZIDES | ROCHE DIAGNOSTICS GMBH (DE) | 2002-12-12 | — | — | WO | disclosed |
| EP-0802916-A1 | LOW MOLECULAR WEIGHT BICYCLIC THROMBIN INHIBITORS | BIOCHEM PHARMA INC (CA) | 1997-10-29 | — | — | EP | disclosed |