Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 8/20 | 0.44 |
| ▸ | TOP2A | P11388 | 2/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752537 | 0.78 | CRBN (0.41) | CRBNTOP2ATOP2BALDH1A1MAPT | |
| SCHEMBL17849857 | 0.77 | PDE3B (0.33) | CRBNPDE3BPDE3A | |
| SCHEMBL18766263 | 0.77 | PDE3B (0.33) | CRBNPDE3BPDE3A | |
| SCHEMBL17849897 | 0.72 | PDE3B (0.31) | PDE3BPDE3A | |
| SCHEMBL9752427 | 0.72 | TOP2A (0.42) | CRBNTOP2ATOP2BALDH1A1MAPT | |
| SCHEMBL9752419 | 0.72 | CRBN (0.35) | CRBNTOP2ATOP2BALDH1A1MAPT | |
| SCHEMBL12111113 | 0.71 | — | — | |
| SCHEMBL12108592 | 0.71 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL12108628 | 0.71 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL12110928 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4892556-A | Process for transfer printing on leather substrates impregnated with aminoplast pre-condensate | SCHULZEN HERBERT W A (DE) | 1990-01-09 | — | — | US | disclosed |
| EP-0226818-A2 | Process for printing on leather substrates | Nortech Chemie GmbH & Co. KG (DE) | 1987-07-01 | — | — | EP | disclosed |