Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524002 | 0.83 | NPC1 (0.44) | LMNANPC1RAB9AKMT2ANPSR1 | |
| SCHEMBL9525705 | 0.83 | NPC1 (0.47) | LMNANPC1RAB9AKMT2ANPSR1 | |
| SCHEMBL9524110 | 0.82 | NPC1 (0.46) | LMNANPC1RAB9AKMT2ANPSR1 | |
| SCHEMBL9525476 | 0.81 | POLB (0.46) | LMNANPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL9525183 | 0.81 | POLB (0.45) | LMNANPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL9526290 | 0.81 | NPC1 (0.44) | LMNANPC1RAB9AKMT2ANPSR1 | |
| SCHEMBL9525526 | 0.80 | POLB (0.44) | LMNANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9525766 | 0.79 | POLB (0.54) | LMNANPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL9524147 | 0.79 | KDM4E (0.44) | LMNANPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL9525255 | 0.79 | KDM4E (0.44) | KMT2ASMN1; SMN2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |