Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.37 |
| ▸ | BCL2 | P10415 | 2/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTR1B | P28222 | 3/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | BAD | Q92934 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524147 | 0.90 | KDM4E (0.44) | KDM4EALDH1A1HPGDHRH4HRH3 | |
| SCHEMBL9524584 | 0.87 | KDM4E (0.41) | KDM4EALDH1A1HPGDHRH4HRH3 | |
| Iodide SCHEMBL9523929 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1HPGDMCL1KMT2A | |
| Hydrochloric Acid SCHEMBL9525954 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1HPGDMCL1KMT2A | |
| SCHEMBL9525095 | 0.80 | CFTR (0.42) | KDM4EALDH1A1HPGDKMT2AHTR1B | |
| SCHEMBL10401410 | 0.79 | LMNA (0.47) | KDM4EALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL9525232 | 0.78 | KDM4E (0.44) | KDM4EALDH1A1HPGDMCL1KMT2A | |
| SCHEMBL9523896 | 0.77 | KDM4E (0.43) | KDM4EALDH1A1HPGDKMT2AHTR1B | |
| SCHEMBL9524400 | 0.76 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDSMN1; SMN2POLB | |
| Iodide SCHEMBL9528125 | 0.76 | KDM4E (0.42) | KDM4EALDH1A1HPGDKMT2AHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0301751-A1 | Pyridinium derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-01 | — | — | EP | disclosed |