Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14999424 | 0.91 | HTR2C (0.69) | HTR2C | |
| SCHEMBL1810242 | 0.83 | HTR2C (0.82) | HTR2CDRD2DRD3HTR6PDE4B | |
| SCHEMBL8049667 | 0.83 | HTR2C (0.82) | HTR2CDRD2DRD3HTR6PDE4B | |
| SCHEMBL8032211 | 0.83 | HTR2C (0.82) | HTR2CDRD2DRD3HTR6PDE4B | |
| Hydrochloric Acid SCHEMBL4573066 | 0.82 | HTR2C (0.82) | HTR2CDRD2HTR6PDE4B | |
| SCHEMBL24792580 | 0.79 | HTR2C (0.56) | HTR2CDRD2DRD3SLC6A2SLC6A4 | |
| SCHEMBL30745377 | 0.79 | HTR2C (0.56) | HTR2CDRD2DRD3SLC6A2SLC6A4 | |
| SCHEMBL8241673 | 0.77 | HTR2C (0.50) | HTR2CDRD2DRD3 | |
| SCHEMBL3854914 | 0.77 | PLG (0.41) | HTR2CDRD2HTR6 | |
| SCHEMBL25240758 | 0.77 | HTR2C (0.54) | HTR2CDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4957927-A | (Diarylmethoxy alkyl)-1-pyrrolidines and piperidines having cardiovascular activity | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1990-09-18 | — | — | US | disclosed |