Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.56 |
| ▸ | HTR1A | P08908 | 5/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.49 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24792580 | 1.00 | HTR2C (0.56) | HTR2CHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21425209 | 0.92 | DRD2 (0.56) | HTR2CSLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL1810242 | 0.83 | HTR2C (0.82) | HTR2CHTR1ADRD2DRD3 | |
| SCHEMBL8049667 | 0.83 | HTR2C (0.82) | HTR2CHTR1ADRD2DRD3 | |
| SCHEMBL8032211 | 0.83 | HTR2C (0.82) | HTR2CHTR1ADRD2DRD3 | |
| SCHEMBL9390227 | 0.82 | KCNH2 (0.48) | HTR2CKCNH2 | |
| SCHEMBL9391575 | 0.82 | CETP (0.50) | HTR2CKCNH2 | |
| SCHEMBL11638505 | 0.81 | KCNH2 (0.51) | HTR2CHTR1ASLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL4573066 | 0.81 | HTR2C (0.82) | HTR2CHTR1ADRD2 | |
| SCHEMBL495697 | 0.79 | SLC18A3 (0.75) | SLC18A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117545748-A | Benzimidazolyl GLP-1GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods of use thereof | 卡莫特医疗有限公司 | 2024-02-09 | — | — | CN | disclosed |