Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | POLB | P06746 | 2/20 | 0.76 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.76 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.76 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.76 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.76 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.59 |
| ▸ | TOP2A | P11388 | 12/20 | 0.54 |
| ▸ | TOP2B | Q02880 | 10/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CLK2 | P49760 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TOP1 | P11387 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10511126 | 0.99 | ALDH1A1 (0.75) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9416068 | 0.88 | ALDH1A1 (0.82) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9416082 | 0.88 | ALDH1A1 (0.82) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL1387312 | 0.88 | ALDH1A1 (0.82) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL8567513 | 0.88 | ALDH1A1 (0.60) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL8567510 | 0.88 | ALDH1A1 (0.60) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL10401207 | 0.88 | KCNH2 (0.74) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9660049 | 0.88 | ALDH1A1 (0.78) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL9416083 | 0.87 | ALDH1A1 (0.80) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL8566510 | 0.87 | ALDH1A1 (0.80) | ALDH1A1POLBOPRM1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302525-A2 | Quinolones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-02-08 | — | — | EP | claimed |
| US-4780468-A | 8-trifluoromethyl quinolones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1988-10-25 | — | — | US | claimed |
| US-4933335-A | Quinolones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1990-06-12 | — | — | US | disclosed |
| EP-0302525-A2 | Quinolones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-02-08 | — | — | EP | disclosed |
| US-4803205-A | Quinolones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-02-07 | — | — | US | disclosed |
| US-4780468-A | 8-trifluoromethyl quinolones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1988-10-25 | — | — | US | disclosed |