Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.68 |
| ▸ | DRD3 | P35462 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | HPGD | P15428 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | ALB | P02768 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312380 | 0.89 | KDM4E (0.84) | KDM4EDRD3ALDH1A1HPGDMEN1 | |
| SCHEMBL10401471 | 0.89 | KDM4E (0.63) | KDM4EDRD3ALDH1A1HPGDMEN1 | |
| SCHEMBL8057366 | 0.88 | KDM4E (0.53) | KDM4EDRD3ALDH1A1HPGDMEN1 | |
| SCHEMBL8058568 | 0.88 | KDM4E (0.52) | KDM4EDRD3ALDH1A1HPGDMEN1 | |
| SCHEMBL8064249 | 0.87 | KDM4E (0.52) | KDM4EDRD3ALDH1A1HPGDMEN1 | |
| SCHEMBL8735575 | 0.86 | KDM4E (0.51) | KDM4EDRD3ALDH1A1HPGDMAPK1 | |
| SCHEMBL10768893 | 0.86 | KDM4E (0.68) | KDM4EDRD3ALDH1A1HPGDMEN1 | |
| SCHEMBL8057426 | 0.85 | KDM4E (0.51) | KDM4EDRD3ALDH1A1HPGDKMT2A | |
| SCHEMBL9773683 | 0.85 | KDM4E (0.67) | KDM4EDRD3ALDH1A1HPGDMEN1 | |
| SCHEMBL8059277 | 0.84 | KDM4E (0.49) | KDM4EDRD3ALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302525-A2 | Quinolones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-02-08 | — | — | EP | claimed |
| US-4803205-A | Quinolones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-02-07 | — | — | US | claimed |
| US-4933335-A | Quinolones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1990-06-12 | — | — | US | disclosed |
| EP-0302525-A2 | Quinolones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-02-08 | — | — | EP | disclosed |
| US-4803205-A | Quinolones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-02-07 | — | — | US | disclosed |
| US-4780468-A | 8-trifluoromethyl quinolones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1988-10-25 | — | — | US | disclosed |