Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434505 | 0.96 | TSHR (0.46) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL10401717 | 0.92 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL16496933 | 0.89 | TSHR (0.40) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL16497052 | 0.89 | TSHR (0.40) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL16497478 | 0.89 | TSHR (0.47) | TSHRLMNATHRBALDH1A1SLC22A1 | |
| SCHEMBL10405207 | 0.89 | TSHR (0.47) | TSHRLMNATHRBALDH1A1SLC22A1 | |
| SCHEMBL1230726 | 0.89 | TSHR (0.40) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL30455702 | 0.86 | TSHR (0.53) | TSHRLMNATHRBALDH1A1SLC22A1 | |
| SCHEMBL30456015 | 0.86 | TSHR (0.53) | TSHRLMNATHRBALDH1A1SLC22A1 | |
| SCHEMBL10401375 | 0.86 | TSHR (0.53) | TSHRLMNATHRBALDH1A1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400618-A2 | Textile lubrication | ETHYL CORPORATION (US) | 1990-12-05 | — | — | EP | disclosed |
| US-4932976-A | Textile lubrication | ETHYL CORPORATION (US) | 1990-06-12 | — | — | US | disclosed |