SCHEMBL434505

SCHEMBL434505

CCCC[Si](CCCC)(CCCC)CCCC

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.46
LMNA P02545 3/20 0.46
THRB P10828 1/20 0.43
ALDH1A1 P00352 4/20 0.35
TDP1 Q9NUW8 1/20 0.35
SLC22A1 O15245 3/20 0.33
SLC22A2 O15244 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
DNM1 Q05193 5/20 0.32
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10401632 0.96 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
SCHEMBL10401717 0.96 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
SCHEMBL16496933 0.93 TSHR (0.40) TSHRLMNATHRBALDH1A1TDP1
SCHEMBL16497478 0.93 TSHR (0.47) TSHRLMNATHRBALDH1A1SLC22A1
SCHEMBL16497052 0.93 TSHR (0.40) TSHRLMNATHRBALDH1A1TDP1
SCHEMBL10405207 0.93 TSHR (0.47) TSHRLMNATHRBALDH1A1SLC22A1
SCHEMBL1230726 0.93 TSHR (0.40) TSHRLMNATHRBALDH1A1TDP1
SCHEMBL30456015 0.89 TSHR (0.53) TSHRLMNATHRBALDH1A1SLC22A1
SCHEMBL30455702 0.89 TSHR (0.53) TSHRLMNATHRBALDH1A1SLC22A1
SCHEMBL10401375 0.89 TSHR (0.53) TSHRLMNATHRBALDH1A1SLC22A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 445 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119612527-A Hollow silicon dioxide microsphere and preparation method thereof 甬江实验室 2025-03-14 CN claimed
CN-117247023-B Method for preparing aerogel by using silicon dioxide 湖北三峡实验室 2024-08-13 CN claimed
US-20240173235-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. 2024-05-30 US claimed
EP-4322915-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS Momentive Performance Materials Inc. (US) 2024-02-21 EP claimed
CN-117425467-A Personal care compositions comprising silicone based 迈图高新材料公司 2024-01-19 CN claimed
CN-117247023-A Method for preparing aerogel by using silicon dioxide 湖北三峡实验室 2023-12-19 CN claimed
WO-2022221354-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2022-10-20 WO claimed
CN-114539630-A Environment-friendly degradable sponge and preparation method thereof 福建大方睡眠科技股份有限公司 2022-05-27 CN claimed
EP-3048088-B1 POROUS CERAMIC MATERIALS FOR INVESTMENT CASTING GEN ELECTRIC (US) 2022-04-20 EP claimed
WO-2022053415-A1 A METHOD OF MODIFYING METALS WITH LASER WYSOKINSKI KAROL (PL) 2022-03-17 WO claimed
US-20150328678-A1 METHODS AND COMPOSITIONS FOR FORMATION OF CERAMIC ARTICLES GENERAL ELECTRIC COMPANY (US) 2015-11-19 US claimed
CN-104745141-A Bi-component condensed type organic silicon pouring sealant as well as preparation method and application thereof SHENZHEN UNITAK ELECTRONIC MATERIALS CO LTD 2015-07-01 CN claimed
CN-102468481-B Method for preparing polyanionic cathode material used for lithium ion battery DALIAN CHEMICAL PHYSICS INST 2014-03-26 CN claimed
CN-102468481-A Method for preparing polyanionic cathode material used for lithium ion battery DALIAN CHEMICAL PHYSICS INST 2012-05-23 CN claimed
US-20070190768-A1 Manufacturing method of semiconductor device KABUSHIKI KAISHA TOSHIBA (JP) 2007-08-16 US claimed
US-20050044778-A1 Fuel compositions employing catalyst combustion structure OCTANE INTERNATIONAL, LTD. 2005-03-03 US claimed
EP-1064994-B1 Dehumidifying material, dehumidifying element and manufacturing method therefor NICHIAS CORP (JP) 2005-01-19 EP claimed
EP-1051461-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR, William C. (US) 2000-11-15 EP claimed
WO-2000050478-A1 NOVEL FORMULATIONS OF ALKYLLITHIUMS WITH IMPROVED THERMAL STABILITY, PROCESSES TO PRODUCE THESE FORMULATIONS AND PROCESSES FOR USING THE SAME TO IMPROVE STABILITY OF LIVING POLYMER CHAIN ENDS FMC CORPORATION (US) 2000-08-31 WO claimed
WO-1999066009-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR WILLIAM C (US) 1999-12-23 WO claimed