Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13878246 | 0.81 | NR4A2 (0.46) | NR4A2PDE10AMEN1KMT2AHRH3 | |
| SCHEMBL3276372 | 0.79 | NR4A2 (0.47) | NR4A2PDE10AKMT2AHRH3HTR3E | |
| SCHEMBL14128956 | 0.78 | PDE10A (0.49) | NR4A2PDE10AMEN1KMT2AHTR3E | |
| SCHEMBL1911781 | 0.77 | NR4A2 (0.46) | NR4A2PDE10AHRH3HTR3EHTR3B | |
| SCHEMBL28887330 | 0.77 | S1PR4 (0.49) | NR4A2PDE10AHRH3HTR3EHTR3B | |
| SCHEMBL29518426 | 0.77 | CCR1 (0.48) | NR4A2PDE10AHRH3HTR3EHTR3B | |
| SCHEMBL7809623 | 0.77 | S1PR4 (0.49) | NR4A2PDE10AKMT2AHRH3HTR3E | |
| SCHEMBL203068 | 0.77 | CCR1 (0.48) | NR4A2PDE10AHRH3HTR3EHTR3B | |
| SCHEMBL4348088 | 0.77 | LOXL2 (0.47) | NR4A2PDE10AHRH3HTR3EHTR3B | |
| SCHEMBL14094658 | 0.76 | PDE10A (0.42) | NR4A2PDE10AMEN1KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4962203-A | ANTIASTHMATIC, ANTIALLERGENIC, ANTIINFLAMMATORY AND CYTOPROTECTIVE AGENTS | MERCK FROST CANADA, INC. (CA) | 1990-10-09 | — | — | US | disclosed |
| EP-0206751-A2 | 2-Substituted quinolines, their preparation and use | MERCK FROSST CANADA INC. (CA) | 1986-12-30 | — | — | EP | disclosed |