Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 9/20 | 0.81 |
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.81 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.51 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.51 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.51 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10401689 | 1.00 | CYSLTR1 (0.81) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL10402879 | 0.90 | CYSLTR1 (0.79) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL10402946 | 0.90 | CYSLTR1 (0.79) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL10402289 | 0.87 | CYSLTR2 (0.62) | CYSLTR1CYSLTR2MEN1KMT2A | |
| SCHEMBL10402290 | 0.87 | CYSLTR2 (0.62) | CYSLTR1CYSLTR2MEN1KMT2A | |
| SCHEMBL9756948 | 0.83 | CYSLTR1 (0.69) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL9756949 | 0.83 | CYSLTR1 (0.69) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL10401656 | 0.83 | CYSLTR1 (0.68) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL10402240 | 0.83 | CYSLTR1 (0.68) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL10402476 | 0.83 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4962203-A | ANTIASTHMATIC, ANTIALLERGENIC, ANTIINFLAMMATORY AND CYTOPROTECTIVE AGENTS | MERCK FROST CANADA, INC. (CA) | 1990-10-09 | — | — | US | disclosed |
| EP-0206751-A2 | 2-Substituted quinolines, their preparation and use | MERCK FROSST CANADA INC. (CA) | 1986-12-30 | — | — | EP | disclosed |