Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 15/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.39 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524757 | 0.85 | TSHR (0.46) | TSHRNPSR1OPRM1OPRK1SLC18A2 | |
| SCHEMBL9526031 | 0.82 | TSHR (0.43) | TSHRNPSR1OPRM1OPRK1SLC18A2 | |
| SCHEMBL10401782 | 0.82 | TSHR (0.51) | TSHRNPSR1OPRM1OPRK1SLC18A2 | |
| SCHEMBL30442509 | 0.80 | TSHR (0.60) | TSHRNPSR1OPRM1OPRK1SLC6A2 | |
| SCHEMBL7694988 | 0.80 | TSHR (0.60) | TSHRNPSR1OPRM1OPRK1SLC6A2 | |
| SCHEMBL30829405 | 0.80 | TSHR (0.60) | TSHRNPSR1OPRM1OPRK1SLC6A2 | |
| SCHEMBL23119015 | 0.77 | TSHR (0.60) | TSHRNPSR1OPRM1OPRK1SLC18A2 | |
| SCHEMBL4853532 | 0.77 | TSHR (0.60) | TSHRNPSR1OPRM1OPRK1SLC18A2 | |
| SCHEMBL9526040 | 0.77 | TSHR (0.42) | TSHRNPSR1OPRM1OPRK1SLC18A2 | |
| Hydrochloric Acid SCHEMBL19953531 | 0.76 | TSHR (0.62) | TSHRNPSR1OPRM1OPRK1SLC18A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |
| US-4959516-A | HEAT RESISTANT SUBSTRATE COATED WITH METAL AND ALLOY PARTICLES IN A POLYMERIC BINDER | DENNISON MANUFACTURING COMPANY (US) | 1990-09-25 | — | — | US | disclosed |
| EP-0301751-A1 | Pyridinium derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-01 | — | — | EP | disclosed |
| US-3956200-A | POLYGLYCOL HYDROGEN POLYPHOSPHONATE | STAUFFER CHEMICAL COMPANY (US) | 1976-05-11 | — | — | US | disclosed |