Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 10/20 | 0.50 |
| ▸ | RECQL | P46063 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | BLM | P54132 | 4/20 | 0.50 |
| ▸ | APEX1 | P27695 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MTOR | P42345 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7192542 | 0.79 | TDP1 (0.50) | TDP1RECQLKDM4EMAPTLMNA | |
| SCHEMBL20361608 | 0.79 | TDP1 (0.50) | TDP1RECQLKDM4EMAPTLMNA | |
| SCHEMBL10403347 | 0.76 | ESR1 (0.42) | TDP1RECQLKDM4EMAPTLMNA | |
| SCHEMBL30516160 | 0.71 | TDP1 (0.67) | TDP1RECQLKDM4EMAPTLMNA | |
| SCHEMBL14293022 | 0.71 | TDP1 (0.67) | TDP1RECQLKDM4EMAPTLMNA | |
| SCHEMBL278495 | 0.71 | TDP1 (0.67) | TDP1RECQLKDM4EMAPTLMNA | |
| SCHEMBL10401987 | 0.71 | TDP1 (0.50) | TDP1RECQLKDM4EMAPTLMNA | |
| Isopropylamine SCHEMBL10604489 | 0.70 | TDP1 (0.70) | TDP1RECQLKDM4EMAPTLMNA | |
| SCHEMBL19771233 | 0.70 | TDP1 (0.70) | TDP1RECQLKDM4EMAPTLMNA | |
| Hydrochloric Acid SCHEMBL1825918 | 0.70 | KDM4E (0.68) | TDP1RECQLKDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |