Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6794454 | 0.85 | LMNA (0.55) | LMNAMAPTPOLBPKMKMT2A | |
| SCHEMBL797506 | 0.81 | SMN1; SMN2 (0.58) | LMNAMAPTPOLBPKMKMT2A | |
| SCHEMBL1665011 | 0.81 | LMNA (0.52) | LMNAMAPTPOLBPKMKMT2A | |
| SCHEMBL9196052 | 0.80 | MAPT (0.53) | LMNAMAPTPOLBPKMKMT2A | |
| SCHEMBL9132981 | 0.80 | LMNA (0.50) | LMNAMAPTPOLBPKMKMT2A | |
| Acetic Acid SCHEMBL21523299 | 0.79 | PTGS1 (0.55) | LMNAMAPTPOLBPKMKMT2A | |
| SCHEMBL10605999 | 0.79 | LMNA (0.57) | LMNAMAPTPOLBPKMKMT2A | |
| SCHEMBL9081470 | 0.78 | LMNA (0.61) | LMNAMAPTPOLBPKMKMT2A | |
| SCHEMBL777803 | 0.78 | ELANE (0.62) | LMNAMAPTPOLBPKMKMT2A | |
| SCHEMBL10404490 | 0.78 | LMNA (0.52) | LMNAMAPTPOLBPKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |