SCHEMBL10403233

SCHEMBL10403233

O=[C]C(=O)Cc1ccccn1

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.51
NPC1 O15118 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.50
PTPRA P18433 1/20 0.47
POLB P06746 1/20 0.46
IDO1 P14902 1/20 0.45
CYP1A2 P05177 2/20 0.45
ALDH1A1 P00352 1/20 0.45
TSHR P16473 1/20 0.45
CYP2C19 P33261 1/20 0.44
FDPS P14324 2/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43
CA5B Q9Y2D0 1/20 0.43
HRH1 P35367 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29236905 0.83 RAB9A (0.50) RAB9ANPC1SMN1; SMN2PTPRAPOLB
SCHEMBL2142240 0.79 RAB9A (0.58) RAB9ANPC1SMN1; SMN2PTPRAPOLB
SCHEMBL6447477 0.78 RAB9A (0.56) RAB9ANPC1SMN1; SMN2PTPRAPOLB
SCHEMBL29676689 0.78 PTPRA (0.56) RAB9ANPC1SMN1; SMN2PTPRAPOLB
Benzene SCHEMBL11747977 0.78 PTPRA (0.56) RAB9ANPC1SMN1; SMN2PTPRAPOLB
SCHEMBL21298 0.78 PTPRA (0.56) RAB9ANPC1SMN1; SMN2PTPRAPOLB
Water SCHEMBL5531145 0.76 PTPRA (0.55) RAB9ANPC1SMN1; SMN2PTPRAPOLB
SCHEMBL988403 0.76 PTPRA (0.55) RAB9ANPC1SMN1; SMN2PTPRAPOLB
SCHEMBL21909733 0.76 RAB9A (0.54) RAB9ANPC1SMN1; SMN2PTPRAPOLB
SCHEMBL5432067 0.76 RAB9A (0.54) RAB9ANPC1SMN1; SMN2PTPRAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4914206-A ANTIBIOTICS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-04-03 US disclosed
EP-0226896-A2 Lankacidin derivatives and production thereof Takeda Chemical Industries, Ltd. (JP) 1987-07-01 EP disclosed