Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | OGA | O60502 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28473803 | 0.82 | MAPT (0.43) | SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL28435235 | 0.82 | MAPT (0.43) | SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL10490784 | 0.81 | MAPT (0.37) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9429259 | 0.80 | POLB (0.34) | SMN1; SMN2 | |
| SCHEMBL10490896 | 0.80 | POLB (0.36) | SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL10530994 | 0.78 | PDE3A (0.38) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10817167 | 0.73 | TDP1 (0.40) | SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL11582652 | 0.73 | POLB (0.41) | SMN1; SMN2 | |
| SCHEMBL11423317 | 0.72 | MAPT (0.39) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9567734 | 0.71 | MAPT (0.46) | SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4940702-A | Cephem compounds | BEECHAM GROUP P.L.C. (GB) | 1990-07-10 | — | — | US | disclosed |
| EP-0211656-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-02-25 | — | — | EP | disclosed |