Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429259 | 0.87 | POLB (0.34) | PDE3AMAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL9429254 | 0.87 | POLB (0.34) | PDE3AMAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10490784 | 0.86 | MAPT (0.37) | PDE3AMAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL28435235 | 0.85 | MAPT (0.43) | PDE3AMAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL28473803 | 0.85 | MAPT (0.43) | PDE3AMAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10543158 | 0.83 | POLB (0.40) | PDE3AMAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL8600205 | 0.83 | POLB (0.40) | PDE3AMAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10493322 | 0.79 | CTSL (0.40) | PDE3AMAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10403829 | 0.78 | SMN1; SMN2 (0.44) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10872366 | 0.78 | KMT2A (0.41) | PDE3AMAPTSLC22A6SLC22A8SLC22A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308559-A2 | Cephalosporins, process for their preparation, pharmaceutical compositions containing them and intermediates | BEECHAM GROUP PLC (GB) | 1989-03-29 | — | — | EP | disclosed |