Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KDM6A | O15550 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM5C | P41229 | 1/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.47 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.47 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 14/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16744334 | 0.78 | CYP2C9 (0.50) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL30982453 | 0.77 | HTT (0.38) | KDM4ECYP2C9CYP2C19ELANEGAA | |
| SCHEMBL30982637 | 0.77 | HTT (0.38) | KDM4ECYP2C9CYP2C19ELANEGAA | |
| SCHEMBL30982936 | 0.77 | HTT (0.38) | KDM4ECYP2C9CYP2C19ELANEGAA | |
| SCHEMBL10403105 | 0.76 | KDM4E (0.46) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL15790433 | 0.73 | CYP2C9 (0.53) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL10403849 | 0.72 | PPID (0.42) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL8662055 | 0.71 | POLB (0.43) | CYP2C19ELANEPOLBGAANPSR1 | |
| SCHEMBL10404483 | 0.71 | KMT2A (0.45) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL30982472 | 0.70 | HTT (0.37) | KDM4ECYP2C9CYP2C19ELANEGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316279-A2 | Ester derivatives of azacyclic hydroxycompounds | CIBA-GEIGY AG (CH) | 1989-05-17 | — | — | EP | claimed |
| US-4908371-A | Pharmaceuticals | CIBA-GEIGY CORPORATION (US) | 1990-03-13 | — | — | US | disclosed |
| EP-0316279-A2 | Ester derivatives of azacyclic hydroxycompounds | CIBA-GEIGY AG (CH) | 1989-05-17 | — | — | EP | disclosed |