Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KDM6A | O15550 | 1/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KDM5C | P41229 | 1/20 | 0.50 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.50 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15790433 | 0.80 | CYP2C9 (0.53) | CYP2C9KDM4EKDM6AKDM4ACYP2C19 | |
| SCHEMBL10404153 | 0.78 | KDM4E (0.47) | CYP2C9KDM4EKDM6AKDM4ACYP2C19 | |
| SCHEMBL17228664 | 0.76 | CYP2C9 (0.48) | CYP2C9KDM4EKDM6AKDM4ACYP2C19 | |
| SCHEMBL15790475 | 0.70 | KDM4E (0.61) | CYP2C9KDM4EKDM6AKDM4ACYP2C19 | |
| SCHEMBL10403105 | 0.69 | KDM4E (0.46) | CYP2C9KDM4EKDM6AKDM4ACYP2C19 | |
| SCHEMBL9986035 | 0.68 | KDM4E (0.41) | CYP2C9KDM4EKDM6AKDM4ACYP2C19 | |
| SCHEMBL9986849 | 0.68 | KDM4E (0.41) | CYP2C9KDM4EKDM6AKDM4ACYP2C19 | |
| Deferiprone SCHEMBL20775057 | 0.67 | KDM4E (1.00) | CYP2C9KDM4EKDM6AKDM4ACYP2C19 | |
| Deferiprone SCHEMBL94474 | 0.67 | KDM4E (1.00) | CYP2C9KDM4EKDM6AKDM4ACYP2C19 | |
| Deferiprone SCHEMBL692741 | 0.65 | KDM4E (0.96) | CYP2C9KDM4EKDM6AKDM4ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150148352-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT ANGINA AND CARDIOVASCULAR CONDITIONS | CELLIX BIO PRIVATE LTD (IN) | 2015-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150148352-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT ANGINA AND CARDIOVASCULAR CONDITIONS | KCNH1, TNNT2, TNNC1 | CYP2C9 234/4885KDM4E 4882/4885KDM6A 4773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.