Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3945193 | 0.93 | REN (0.33) | REN | |
| SCHEMBL3945188 | 0.93 | REN (0.33) | REN | |
| SCHEMBL4533308 | 0.88 | REN (0.39) | REN | |
| SCHEMBL4533306 | 0.88 | REN (0.39) | REN | |
| SCHEMBL1038201 | 0.87 | AXL (0.37) | RENAXLMERTK | |
| SCHEMBL1040426 | 0.86 | REN (0.35) | RENAXLMERTK | |
| SCHEMBL1039721 | 0.85 | AXL (0.37) | RENAXLMERTK | |
| SCHEMBL1035648 | 0.85 | AXL (0.35) | RENAXLMERTK | |
| SCHEMBL1040564 | 0.84 | REN (0.32) | RENAXLMERTK | |
| SCHEMBL1040425 | 0.84 | REN (0.30) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049514-B1 | NITRATE ESTERS OF PIPERIDINES | NOVARTIS AG (CH) | 2011-01-26 | — | — | EP | disclosed |