SCHEMBL10404342

SCHEMBL10404342

Cc1c(C)c(C(=O)O)c(O)c(O)c1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 7/20 0.52
LDHB P07195 7/20 0.52
DPP4 P27487 1/20 0.44
CYP3A4 P08684 2/20 0.41
ACHE P22303 1/20 0.41
GLRA3 O75311 1/20 0.41
GLRB P48167 1/20 0.41
MAPT P10636 1/20 0.39
ALB P02768 3/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
NOTUM Q6P988 1/20 0.37
GRM1 Q13255 1/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5590144 0.92 LDHA (0.57) LDHALDHBDPP4CYP3A4ACHE
SCHEMBL19193900 0.88 LDHA (0.54) LDHALDHBDPP4CYP3A4ACHE
SCHEMBL8830267 0.88 LDHA (0.48) LDHALDHBDPP4CYP3A4ACHE
SCHEMBL7577609 0.88 LDHA (0.46) LDHALDHBDPP4CYP3A4ACHE
SCHEMBL274096 0.86 LDHA (0.42) LDHALDHBDPP4CYP3A4ACHE
SCHEMBL29434000 0.86 LDHA (0.42) LDHALDHBDPP4CYP3A4ACHE
SCHEMBL5587007 0.85 LDHA (0.42) LDHALDHBDPP4CYP3A4ACHE
SCHEMBL5589377 0.85 DPP4 (0.45) LDHALDHBDPP4CYP3A4ACHE
SCHEMBL5589356 0.85 LDHA (0.42) LDHALDHBDPP4CYP3A4ACHE
SCHEMBL5589466 0.85 LDHA (0.42) LDHALDHBDPP4CYP3A4ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114478243-A Method for synthesizing dihydroxy dimethyl terephthalate by oxygen catalytic oxidation method 常州大学 2022-05-13 CN claimed
US-4939254-A Template synthesis of macrocyclic catecholamide complexes THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1990-07-03 US disclosed