Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10402301 | 0.83 | MCL1 (0.52) | MCL1POLBGPR35CYP2D6CDC25B | |
| SCHEMBL10401957 | 0.80 | MCL1 (0.55) | MCL1POLBGPR35CYP2D6CSF1R | |
| SCHEMBL10080476 | 0.74 | MEN1 (0.61) | MCL1POLBGPR35CYP2D6GRIK1 | |
| SCHEMBL24895076 | 0.74 | POLB (0.58) | POLBGPR35AKR1C2CYP2D6CDC25B | |
| Anthracene SCHEMBL7269976 | 0.74 | MAPK8 (0.63) | AKR1C3AKR1C2MAPK8MAPTGFER | |
| SCHEMBL24283538 | 0.72 | MCL1 (0.61) | MCL1P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL4245559 | 0.71 | MAPK8 (0.67) | AKR1C3AKR1C2MAPK8MAPTTAS2R14 | |
| SCHEMBL18392237 | 0.71 | MCL1 (1.00) | MCL1 | |
| SCHEMBL29539796 | 0.71 | MCL1 (1.00) | MCL1 | |
| SCHEMBL2786936 | 0.70 | MCL1 (0.58) | MCL1AKR1C3AKR1C2MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4913997-A | PHOTOSENSITIVE LAYER CONTAINING AZO PIGMENTS, HIGH DIRABILITY, MOISTURE RESISTANCE, THERMAL STABILITY | MITSUBISHI PAPER MILLS LIMITED (JP) | 1990-04-03 | — | — | US | disclosed |