Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | MPL | P40238 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10080459 | 0.81 | MPL (0.48) | MEN1KMT2ARXFP1MPLALDH1A1 | |
| SCHEMBL7672350 | 0.81 | NR4A1 (0.52) | MEN1KMT2ARXFP1ALDH1A1HPGD | |
| SCHEMBL522958 | 0.80 | MEN1 (0.71) | MEN1KMT2ARXFP1ALDH1A1HPGD | |
| SCHEMBL2853503 | 0.76 | MEN1 (1.00) | MEN1KMT2ARXFP1ALDH1A1HPGD | |
| SCHEMBL10946505 | 0.75 | MEN1 (0.65) | MEN1KMT2ARXFP1ALDH1A1HPGD | |
| SCHEMBL10404609 | 0.74 | MCL1 (0.55) | GRIK1GPR35MCL1POLBTAS2R14 | |
| SCHEMBL28192328 | 0.74 | KIF11 (0.59) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL2845799 | 0.74 | MEN1 (0.63) | MEN1KMT2ARXFP1ALDH1A1HPGD | |
| SCHEMBL8635085 | 0.74 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL29534764 | 0.74 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019106-A2 | POSITIVE AND NEGATIVE MODULATORS OF NMDA RECEPTORS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2012-02-09 | — | — | WO | disclosed |