Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.41 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10405169 | 1.00 | CYP24A1 (0.44) | CYP24A1CYP11B1CYP11B2GPR132FAAH | |
| SCHEMBL10660559 | 0.79 | CYP24A1 (0.43) | CYP24A1FAAHMGLLCYP26A1KDM4E | |
| SCHEMBL9471581 | 0.79 | CYP11B1 (0.40) | CYP24A1CYP11B1CYP11B2FAAHMGLL | |
| SCHEMBL9913370 | 0.77 | KDM4E (0.44) | CYP24A1CYP26A1KDM4E | |
| SCHEMBL4256422 | 0.76 | QPCT (0.39) | CYP24A1 | |
| SCHEMBL29793498 | 0.72 | HDAC3 (0.47) | GPR132KDM4E | |
| Imidazole-1-Carboxylic Acid Phenylamide SCHEMBL10668282 | 0.72 | RAB9A (0.50) | FAAHMGLLKDM4E | |
| SCHEMBL23455649 | 0.72 | SMN1; SMN2 (0.54) | CYP19A1 | |
| SCHEMBL21807366 | 0.71 | HDAC3 (0.46) | GPR132KDM4E | |
| SCHEMBL28250865 | 0.71 | HDAC3 (0.46) | GPR132KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4929736-A | INHIBITORS OF ELASTASE, AZOLIDES | BOARD OF TRUSTEES OF THE WICHITA STATE UNIVERSITY (US) | 1990-05-29 | — | — | US | disclosed |