⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053140 | 0.80 | — | — | |
| SCHEMBL1241816 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL1423725 | 0.71 | TSHR (0.37) | — | |
| SCHEMBL21541293 | 0.71 | — | — | |
| Iodide SCHEMBL9422924 | 0.71 | TSHR (0.37) | — | |
| SCHEMBL16801428 | 0.69 | — | — | |
| SCHEMBL360449 | 0.69 | — | — | |
| SCHEMBL2959660 | 0.69 | — | — | |
| SCHEMBL9946494 | 0.69 | — | — | |
| SCHEMBL4940618 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2269985-A2 | Substituted tetracycline compounds | Paratek Pharmaceuticals, Inc. (US) | 2011-01-05 | — | — | EP | claimed |
| EP-1807387-A2 | SUBSTITUTED TETRACYCLINE COMPOUNDS | Paratek Pharmaceuticals, Inc. (US) | 2007-07-18 | — | — | EP | claimed |
| WO-2006047756-A2 | SUBSTITUTED TETRACYCLINE COMPOUNDS | PARATEK PHARMACEUTICALS, INC. (US) | 2006-05-04 | — | — | WO | claimed |
| US-20160145242-A1 | PHENYLIMIDAZOLE DERIVATIVE, AND THERAPEUTIC MEDICINE OR PREVENTIVE MEDICINE FOR INFLAMMATORY DISEASE, ETC. | NIPPON SODA CO., LTD. (JP) | 2016-05-26 | — | — | US | disclosed |
| EP-2998298-A1 | PHENYLIMIDAZOLE DERIVATIVE, AND THERAPEUTIC MEDICINE OR PREVENTIVE MEDICINE FOR INFLAMMATORY DISEASE, ETC. | Nippon Soda Co., Ltd. (JP) | 2016-03-23 | — | — | EP | disclosed |
| EP-2949644-A2 | SUBSTITUTED TETRACYCLINE COMPOUNDS | Paratek Pharmaceuticals, Inc. (US) | 2015-12-02 | — | — | EP | disclosed |
| US-20140155357-A1 | SUBSTITUTED TETRACYCLINE COMPOUNDS | PARATEK PHARMACEUTICALS, INC. | 2014-06-05 | — | — | US | disclosed |
| US-8466132-B2 | Bactericides; antitumor agents; modulation of gene expression; malaria therapy; viricides; parasiticides; multiple sclerosis | PARATEK PHARMACEUTICALS, INC. (US) | 2013-06-18 | — | — | US | disclosed |
| EP-2305637-A2 | Substituted tetracycline compounds | Paratek Pharmaceuticals, Inc. (US) | 2011-04-06 | — | — | EP | disclosed |
| EP-2295419-A2 | Substituted tetracycline compounds | Paratek Pharmaceuticals, Inc. (US) | 2011-03-16 | — | — | EP | disclosed |
| EP-2287140-A2 | Substituted tetracycline compounds | Paratek Pharmaceuticals, Inc. (US) | 2011-02-23 | — | — | EP | disclosed |
| EP-2284164-A2 | Substituted tetracycline compounds | Paratek Pharmaceuticals, Inc. (US) | 2011-02-16 | — | — | EP | disclosed |
| EP-2269978-A2 | Substituted tetracycline compounds | Paratek Pharmaceuticals, Inc. (US) | 2011-01-05 | — | — | EP | disclosed |
| EP-2269991-A2 | Substituted tetracycline compounds | Paratek Pharmaceuticals, Inc. (US) | 2011-01-05 | — | — | EP | disclosed |
| EP-2269985-A2 | Substituted tetracycline compounds | Paratek Pharmaceuticals, Inc. (US) | 2011-01-05 | — | — | EP | disclosed |
| EP-2033950-A1 | Substituted tetracycline compounds | Paratek Pharmaceuticals, Inc. (US) | 2009-03-11 | — | — | EP | disclosed |
| EP-1807387-A2 | SUBSTITUTED TETRACYCLINE COMPOUNDS | Paratek Pharmaceuticals, Inc. (US) | 2007-07-18 | — | — | EP | disclosed |
| US-20060166945-A1 | Substituted tetracycline compounds | PARATEK PHARMACEUTICALS, INC. (US) | 2006-07-27 | — | — | US | disclosed |
| WO-2006047756-A2 | SUBSTITUTED TETRACYCLINE COMPOUNDS | PARATEK PHARMACEUTICALS, INC. (US) | 2006-05-04 | — | — | WO | disclosed |
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |