⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11362775 | 0.97 | — | — | |
| SCHEMBL6244025 | 0.81 | — | — | |
| SCHEMBL7870141 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL7963708 | 0.79 | — | — | |
| SCHEMBL19838222 | 0.77 | ALDH1A1 (0.48) | — | |
| Hydrochloric Acid SCHEMBL11360713 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL11365644 | 0.75 | ALDH1A1 (0.47) | — | |
| SCHEMBL1241816 | 0.72 | — | — | |
| SCHEMBL11152228 | 0.72 | ALDH1A1 (0.44) | — | |
| Hydrochloric Acid SCHEMBL1423725 | 0.69 | TSHR (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192720-A1 | MACROCYCLIC COMPOUNDS | ZENO MANAGEMENT, INC. | 2023-06-22 | — | — | US | disclosed |
| CN-108456216-A | Sulfonyl hydrazines compound and application thereof | 上海长森药业有限公司 | 2018-08-28 | — | — | CN | disclosed |
| US-7838220-B2 | T cell regulatory genes associated with immune disease | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2010-11-23 | — | — | US | disclosed |
| US-7763624-B2 | Substituted pyrazolo[3,4-d]pyrimidines as ACK-1 and LCK inhibitors | AMGEN INC. (US) | 2010-07-27 | — | — | US | disclosed |
| EP-1926734-A1 | PYRAZOLOPYRIDINE AND PYRAZOLOPYRIMIDINE COMPOUNDS USEFUL AS KINASE ENZYMES MODULATORS | Amgen Inc. (US) | 2008-06-04 | — | — | EP | disclosed |
| WO-2008001182-A1 | TRICYCLIC HETEROARYL COMPOUNDS AS PDE10 INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-01-03 | — | — | WO | disclosed |
| US-20070072851-A1 | Pyrazolopyridine and pyrazolopyrimidine compounds | AMGEN INC. (US) | 2007-03-29 | — | — | US | disclosed |
| WO-2007024680-A1 | PYRAZOLOPYRIDINE AND PYRAZOLOPYRIMIDINE COMPOUNDS USEFUL AS KINASE ENZYMES MODULATORS | AMGEN INC. (US) | 2007-03-01 | — | — | WO | disclosed |