Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.43 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23882891 | 0.78 | BRD4 (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL11075725 | 0.78 | UHRF1 (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL10514041 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAKDM4EKDM5AALDH1A1 | |
| SCHEMBL15922040 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAKDM4EKDM5AALDH1A1 | |
| SCHEMBL6378754 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAKDM4EKDM5AALDH1A1 | |
| SCHEMBL19846691 | 0.76 | UHRF1 (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL17198732 | 0.76 | UHRF1 (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL20247131 | 0.75 | UHRF1 (0.46) | KDM4EPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3660321 | 0.74 | PSEN1 (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL13754944 | 0.74 | NR3C2 (0.47) | LMNAKDM4EPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4931450-A | Amino acid derivatives | NOVO INDUSTRI A/S (DK) | 1990-06-05 | — | — | US | disclosed |