Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RHOA | P61586 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14587496 | 0.83 | CA12 (0.44) | ALDH1A1NPSR1CYP3A4TSHRCYP1A2 | |
| SCHEMBL17662056 | 0.80 | ALDH1A1 (0.56) | ALDH1A1NPSR1RHOACYP3A4POLB | |
| SCHEMBL10542563 | 0.78 | ALDH1A1 (0.41) | ALDH1A1POLBCYP1A2CYP2C9MAPT | |
| SCHEMBL9143592 | 0.78 | ALDH1A1 (0.41) | ALDH1A1CYP1A2CYP2C9MAPTGAA | |
| SCHEMBL17662067 | 0.78 | ALDH1A1 (0.53) | ALDH1A1NPSR1RHOACYP3A4POLB | |
| SCHEMBL10548122 | 0.77 | ALDH1A1 (0.38) | ALDH1A1CYP1A2CYP2C9MAPTGAA | |
| SCHEMBL10851006 | 0.77 | ALDH1A1 (0.40) | ALDH1A1CYP1A2CYP2C9MAPTGAA | |
| SCHEMBL30660870 | 0.77 | ALDH1A1 (0.40) | ALDH1A1CYP1A2CYP2C9MAPTGAA | |
| SCHEMBL9425523 | 0.75 | ALDH1A1 (0.46) | ALDH1A1HSD17B10CYP1A2CYP2C9MAPT | |
| SCHEMBL29565442 | 0.75 | ALDH1A1 (0.46) | ALDH1A1HSD17B10CYP1A2CYP2C9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4966900-A | FOR MICROBISM THERAPY, BACTERIAL INFECTIONS | SANKEI PHARMACEUTICAL COMPANY LTD. (JP) | 1990-10-30 | — | — | US | disclosed |
| EP-0286145-A2 | 3-Heterocyclylthiomethyl cephalosporins | SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) | 1988-10-12 | — | — | EP | disclosed |
| EP-0254495-A2 | Beta-Lactam compound, method for preparing the same, medicinal composition for bacterially infectious disease therapy containing the same and intermediates for synthesis of the same | SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) | 1988-01-27 | — | — | EP | disclosed |