Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 4/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 3/20 | 0.38 |
| ▸ | MARK2 | Q7KZI7 | 2/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10408157 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1MAP2K1CLK4DYRK1B | |
| SCHEMBL2462603 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1MAP2K1CLK4DYRK1B | |
| SCHEMBL359062 | 0.79 | KDM4E (0.57) | KDM4EALDH1A1MAP2K1CLK4DYRK1B | |
| SCHEMBL23728533 | 0.77 | KDM4E (0.54) | KDM4EALDH1A1MAP2K1CLK4DYRK1B | |
| SCHEMBL29961700 | 0.76 | KDM4E (0.52) | KDM4EALDH1A1MAP2K1CLK4DYRK1B | |
| SCHEMBL23728541 | 0.76 | HSD11B1 (0.53) | KDM4EALDH1A1MAP2K1CLK4DYRK1B | |
| SCHEMBL18208300 | 0.76 | KDM4E (0.56) | KDM4EALDH1A1MAP2K1CLK4DYRK1B | |
| SCHEMBL23744975 | 0.76 | KDM4E (0.52) | KDM4EALDH1A1MAP2K1CLK4DYRK1B | |
| SCHEMBL23744951 | 0.74 | KDM4E (0.61) | KDM4EALDH1A1MAP2K1CLK4DYRK1B | |
| SCHEMBL31278235 | 0.72 | MAP2K1 (0.63) | KDM4EALDH1A1MAP2K1CLK4DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4966900-A | FOR MICROBISM THERAPY, BACTERIAL INFECTIONS | SANKEI PHARMACEUTICAL COMPANY LTD. (JP) | 1990-10-30 | — | — | US | disclosed |
| EP-0254495-A2 | Beta-Lactam compound, method for preparing the same, medicinal composition for bacterially infectious disease therapy containing the same and intermediates for synthesis of the same | SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) | 1988-01-27 | — | — | EP | disclosed |