Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | TACR2 | P21452 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10408120 | 1.00 | PDE4D (0.49) | PDE4DTACR2SLC6A2TSHRCYP2C19 | |
| SCHEMBL10408205 | 0.92 | PDE4D (0.51) | PDE4DTACR2SLC6A2TSHRCYP2C19 | |
| SCHEMBL10408203 | 0.92 | PDE4D (0.51) | PDE4DTACR2SLC6A2TSHRCYP2C19 | |
| SCHEMBL6298186 | 0.90 | PDE4D (0.46) | PDE4DTACR2SLC6A2TSHRCYP2C19 | |
| SCHEMBL10352583 | 0.88 | HTR1A (0.51) | PDE4DTACR2HTR1ANT5EPTPN1 | |
| SCHEMBL10400344 | 0.88 | HTR1A (0.51) | PDE4DTACR2HTR1ANT5EPTPN1 | |
| SCHEMBL21657197 | 0.87 | HTR1A (0.50) | PDE4DTACR2HTR1ANT5EPTPN1 | |
| SCHEMBL25084148 | 0.85 | PTPN1 (0.47) | SLC6A2PDPK1MTORPTPN1CDC25B | |
| SCHEMBL10408745 | 0.84 | HTR1A (0.53) | PDE4DTACR2SLC6A2HTR1ANT5E | |
| SCHEMBL10408744 | 0.84 | HTR1A (0.53) | PDE4DTACR2SLC6A2HTR1ANT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968790-A | HYPOGLYCEMIC AGENTS, PLANT GROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1990-11-06 | — | — | US | disclosed |