Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10408089 | 0.91 | PDE4D (0.40) | SLC6A2PDPK1MTORTSHRCYP2C19 | |
| SCHEMBL10408088 | 0.91 | PDE4D (0.40) | SLC6A2PDPK1MTORTSHRCYP2C19 | |
| SCHEMBL10351785 | 0.87 | BCHE (0.42) | PDPK1MTORTSHRPDE4DTACR2 | |
| SCHEMBL10425591 | 0.87 | BCHE (0.42) | PDPK1MTORTSHRPDE4DTACR2 | |
| SCHEMBL10408162 | 0.85 | ALDH1A1 (0.43) | SLC6A2PDPK1MTORTSHRCYP2C19 | |
| SCHEMBL10352260 | 0.81 | BCHE (0.40) | PDPK1MTORPDE4DTACR2BCHE | |
| SCHEMBL10351542 | 0.81 | BCHE (0.40) | PDPK1MTORPDE4DTACR2BCHE | |
| SCHEMBL10352256 | 0.79 | PDPK1 (0.43) | SLC6A2PDPK1MTORTSHRCYP2C19 | |
| SCHEMBL10352257 | 0.79 | PDPK1 (0.43) | SLC6A2PDPK1MTORTSHRCYP2C19 | |
| SCHEMBL4238214 | 0.79 | TSHR (0.40) | SLC6A2PDPK1MTORTSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968790-A | HYPOGLYCEMIC AGENTS, PLANT GROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1990-11-06 | — | — | US | disclosed |
| EP-0354323-A2 | Antidiabetic phosphates | AMERICAN CYANAMID COMPANY (US) | 1990-02-14 | — | — | EP | disclosed |