Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 4/20 | 0.51 |
| ▸ | PTAFR | P25105 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.43 |
| ▸ | HRH1 | P35367 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.43 |
| ▸ | HTR2B | P41595 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10408874 | 0.85 | SETD7 (0.54) | SETD7KCNH2CHRM2HTR1ACHRM1 | |
| SCHEMBL11600653 | 0.82 | PTAFR (0.52) | SETD7PTAFRKCNH2CHRM2HTR1A | |
| SCHEMBL10409954 | 0.78 | PTAFR (0.48) | SETD7PTAFRKCNH2CHRM2HTR1A | |
| SCHEMBL10465365 | 0.78 | PTAFR (0.48) | SETD7PTAFRKCNH2CHRM2HTR1A | |
| SCHEMBL10409953 | 0.75 | SETD7 (0.67) | SETD7KCNH2CHRM2HTR1ACHRM1 | |
| SCHEMBL10465366 | 0.74 | PTAFR (0.42) | SETD7PTAFRKCNH2CHRM2HTR1A | |
| SCHEMBL10409038 | 0.72 | SETD7 (0.45) | SETD7PTAFRKCNH2CHRM2HTR1A | |
| SCHEMBL6808721 | 0.71 | SETD7 (0.65) | SETD7PTAFRKCNH2CHRM2HTR1A | |
| SCHEMBL7817056 | 0.70 | SETD7 (1.00) | SETD7PTAFRKCNH2CHRM2HTR1A | |
| SCHEMBL9035820 | 0.70 | SETD7 (0.73) | SETD7PTAFRKCNH2CHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4929621-A | ANTIDEPRESSANTS, ANXIOLYTIC AGENTS | SYNTHELABO (FR) | 1990-05-29 | — | — | US | disclosed |
| US-4891376-A | MIGRAINE | SYNTHELABO (FR) | 1990-01-02 | — | — | US | disclosed |