Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 5/20 | 0.48 |
| ▸ | HRH1 | P35367 | 11/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10409954 | 0.81 | PTAFR (0.48) | PTAFRHRH1KCNH2CHRM2HTR1A | |
| SCHEMBL10408879 | 0.78 | SETD7 (0.51) | PTAFRHRH1KCNH2CHRM2HTR1A | |
| SCHEMBL10465366 | 0.76 | PTAFR (0.42) | PTAFRHRH1KCNH2CHRM2HTR1A | |
| SCHEMBL11600653 | 0.76 | PTAFR (0.52) | PTAFRHRH1KCNH2CHRM2HTR1A | |
| SCHEMBL10409037 | 0.68 | SETD7 (0.48) | PTAFRHRH1KCNH2CHRM2HTR1A | |
| SCHEMBL10409038 | 0.67 | SETD7 (0.45) | PTAFRHRH1KCNH2CHRM2HTR1A | |
| SCHEMBL6808721 | 0.66 | SETD7 (0.65) | PTAFRHRH1KCNH2CHRM2HTR1A | |
| SCHEMBL14825803 | 0.66 | HRH1 (0.65) | PTAFRHRH1KCNH2CHRM2HTR1A | |
| SCHEMBL7817056 | 0.65 | SETD7 (1.00) | PTAFRHRH1KCNH2CHRM2HTR1A | |
| SCHEMBL9832197 | 0.65 | PTAFR (0.76) | PTAFRHRH1KCNH2CHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4929621-A | ANTIDEPRESSANTS, ANXIOLYTIC AGENTS | SYNTHELABO (FR) | 1990-05-29 | — | — | US | disclosed |