Formic Acid Methyl Ester

Formic Acid Methyl Ester

SCHEMBL10409083

CCCNCCC.COC=O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 3/20 0.46
ADH1A P07327 3/20 0.46
ADH7 P40394 3/20 0.46
PAOX Q6QHF9 1/20 0.39
ALDH1A1 P00352 3/20 0.36
TSHR P16473 1/20 0.36
ADH1C P00326 2/20 0.36
EPHX1 P07099 2/20 0.35
ADH4 P08319 1/20 0.35
CA1 P00915 1/20 0.33
ANPEP P15144 1/20 0.32
MEN1 O00255 1/20 0.30
GLA P06280 1/20 0.30
CYP2C19 P33261 1/20 0.30
KMT2A Q03164 1/20 0.30
MAPK1 P28482 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butane SCHEMBL27882895 0.81
Formic Acid Methyl Ester SCHEMBL28432367 0.79 TSHR (0.62) ADH1BADH1AADH7ALDH1A1TSHR
Formic Acid Methyl Ester SCHEMBL27748266 0.77
SCHEMBL17626634 0.77 TSHR (0.53) ADH1BADH1AADH7PAOXALDH1A1
SCHEMBL15445 0.77
SCHEMBL6196103 0.76
Hexane SCHEMBL2754293 0.75 TSHR (0.48) ADH1BADH1AADH7ALDH1A1TSHR
Pentane SCHEMBL8157918 0.75
Formic Acid SCHEMBL3541955 0.75 ADH1B (0.50) ADH1BADH1AADH7PAOXALDH1A1
Formic Acid Methyl Ester SCHEMBL28252004 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4958026-A HYPOTENSIVE AGENTS SCHERING AKTIENGESLLSCHAFT (DE) 1990-09-18 US disclosed