SCHEMBL10409284

SCHEMBL10409284

CCCCCNc1ccc(Br)cc1CC

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.49
CYP1A2 P05177 3/20 0.42
CYP2D6 P10635 3/20 0.42
CYP2C19 P33261 3/20 0.42
HDAC3 O15379 2/20 0.42
HDAC1 Q13547 2/20 0.42
HDAC2 Q92769 2/20 0.42
ABL1 P00519 1/20 0.42
HCAR3 P49019 1/20 0.42
LMNA P02545 1/20 0.41
POLB P06746 1/20 0.41
MAPK1 P28482 1/20 0.40
NPY1R P25929 1/20 0.40
NPY2R P49146 1/20 0.40
MGLL Q99685 1/20 0.40
APEX1 P27695 1/20 0.39
CNR1 P21554 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10408673 0.98 CNR2 (0.48) CNR2CYP1A2CYP2D6CYP2C19HDAC3
SCHEMBL10408187 0.98 CNR2 (0.48) CNR2CYP1A2CYP2D6CYP2C19HDAC3
SCHEMBL10407968 0.89 CNR2 (0.45) CNR2CYP1A2CYP2D6CYP2C19HDAC3
SCHEMBL10408700 0.87 CNR2 (0.44) CNR2CYP1A2CYP2D6CYP2C19HDAC3
SCHEMBL10407902 0.87 CNR2 (0.44) CNR2CYP1A2CYP2D6CYP2C19HDAC3
SCHEMBL10409245 0.83 CNR2 (0.41) CNR2CYP1A2CYP2D6CYP2C19HDAC3
SCHEMBL10408256 0.83 ALDH1A1 (0.40) CNR2LMNAPOLBMAPK1MGLL
SCHEMBL10408210 0.83 PTGER4 (0.46) CNR2LMNAMAPK1
SCHEMBL10409262 0.82 ALDH1A1 (0.48) CNR2LMNAMAPK1APEX1
SCHEMBL8293173 0.80 MAPK1 (0.44) CYP1A2CYP2D6CYP2C19LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4925984-A REACTION WITH BROMINE IN SOLUTION ETHYL CORPORATION (US) 1990-05-15 US disclosed