SCHEMBL10411367

SCHEMBL10411367

C=C(C)C(=O)C(=O)CC[SiH3]

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.33
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9849272 0.77 TDP1 (0.35) TDP1ALDH1A1
SCHEMBL9616888 0.77 TDP1 (0.35) TDP1ALDH1A1
SCHEMBL28585686 0.71 CES1 (0.34) TDP1
SCHEMBL5137154 0.70
SCHEMBL10435380 0.70
Hydrochloric Acid SCHEMBL8166002 0.70 ACHE (0.41) ALDH1A1
SCHEMBL7019166 0.70 PTGS1 (0.32)
SCHEMBL9407187 0.70 CES1 (0.39)
SCHEMBL16099432 0.69 CYP2D6 (0.36) TDP1ALDH1A1
SCHEMBL8503742 0.69 KDM4E (0.34) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4906446-A Filler for dental materials and dental materials containing the same BARD AUTOTRANSFUSION ACQUISITION CORPORATION 1990-03-06 US disclosed