Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PER2 | O15055 | 1/20 | 0.34 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18821137 | 0.77 | TSHR (0.48) | TSHRMAPTPER2CRY2PGR | |
| SCHEMBL23102951 | 0.75 | TSHR (0.47) | TSHRMAPTPGRPOLB | |
| SCHEMBL11997282 | 0.74 | TSHR (0.60) | TSHRMAPTPOLBSMN1; SMN2 | |
| SCHEMBL14145690 | 0.72 | TSHR (0.48) | TSHRMAPTPGRPOLB | |
| SCHEMBL21881956 | 0.72 | TSHR (0.45) | TSHRMAPTPGRPOLB | |
| SCHEMBL21881994 | 0.72 | TSHR (0.45) | TSHRMAPTPGRPOLB | |
| SCHEMBL19338364 | 0.71 | MAPT (0.44) | TSHRMAPTPOLBSMN1; SMN2 | |
| SCHEMBL11997219 | 0.71 | MAPT (0.72) | TSHRMAPTPOLBSMN1; SMN2 | |
| SCHEMBL12741627 | 0.71 | MAPT (0.72) | TSHRMAPTPOLBSMN1; SMN2 | |
| SCHEMBL14145833 | 0.71 | TSHR (0.60) | TSHRMAPTPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4978744-A | Synthesis of dolastatin 10 | ARIZONA BOARD OF REGENTS (US) | 1990-12-18 | — | — | US | disclosed |