Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12667143 | 0.85 | MAPT (0.66) | BRD4MAPTGAAALDH1A1POLB | |
| SCHEMBL11622652 | 0.85 | MAPT (0.66) | BRD4MAPTGAAALDH1A1POLB | |
| SCHEMBL14145833 | 0.83 | TSHR (0.60) | TSHRMAPTGAAPOLBSMN1; SMN2 | |
| SCHEMBL8292878 | 0.83 | MAPT (0.72) | TSHRMAPTGAAPOLBSMN1; SMN2 | |
| SCHEMBL11997219 | 0.83 | MAPT (0.72) | TSHRMAPTGAAPOLBSMN1; SMN2 | |
| SCHEMBL12741627 | 0.83 | MAPT (0.72) | TSHRMAPTGAAPOLBSMN1; SMN2 | |
| SCHEMBL563946 | 0.82 | BRD4 (0.53) | TSHRBRD4MAPTGAAALDH1A1 | |
| SCHEMBL562860 | 0.82 | BRD4 (0.53) | TSHRBRD4MAPTGAAALDH1A1 | |
| SCHEMBL19295649 | 0.82 | BRD4 (0.55) | TSHRBRD4MAPTGAAALDH1A1 | |
| SCHEMBL12846946 | 0.81 | TSHR (0.66) | TSHRMAPTALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289975-B1 | Organopolysiloxane compound and amidoamine compound, and cosmetic preparation | SHINETSU CHEMICAL CO (JP) | 2012-08-22 | — | — | EP | disclosed |
| US-20110052523-A1 | ORGANOPOLYSILOXANE COMPOUND AND AMIDOAMINE COMPOUND, AND COSMETIC PREPARATION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-03-03 | — | — | US | disclosed |
| EP-2289975-A2 | Organopolysiloxane compound and amidoamine compound, and cosmetic preparation | Shin-Etsu Chemical Co., Ltd. (JP) | 2011-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110052523-A1 | ORGANOPOLYSILOXANE COMPOUND AND AMIDOAMINE COMPOUND, AND COSMETIC PREPARATION | H1-3, H1-0, H1-2 | TSHR 758/4885BRD4 3403/4885MAPT 4442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.