Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | ATP4A | P20648 | 1/20 | 0.38 |
| ▸ | ATP4B | P51164 | 1/20 | 0.38 |
| ▸ | PDE9A | O76083 | 1/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10411402 | 0.91 | FFAR4 (0.42) | FFAR4MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL10411557 | 0.90 | FFAR4 (0.41) | FFAR4MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL10411924 | 0.88 | PDE9A (0.43) | MAPTMAPK1TDP1L3MBTL1PRMT5 | |
| SCHEMBL10412617 | 0.81 | ABCB1 (0.45) | ADORA3 | |
| SCHEMBL10411403 | 0.81 | PDE4A (0.43) | FFAR4MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL2530644 | 0.80 | PDE9A (0.49) | MAPK1TDP1HTTSMN1; SMN2PDE9A | |
| SCHEMBL10410753 | 0.80 | PRMT5 (0.55) | MAPTMAPK1TDP1L3MBTL1PRMT5 | |
| SCHEMBL10411926 | 0.78 | — | — | |
| SCHEMBL6376433 | 0.74 | PDE4A (0.45) | MAPTSMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL9007521 | 0.72 | PARP1 (0.41) | MAPTMAPK1TDP1L3MBTL1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4925853-A | Antiinflammatory, antiallergens, antiulcer agents | BEECHAM GROUP PLC (GB) | 1990-05-15 | — | — | US | disclosed |
| EP-0178413-A1 | Benzimidazoles | BEECHAM GROUP PLC (GB) | 1986-04-23 | — | — | EP | disclosed |