Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 10/20 | 0.55 |
| ▸ | DHODH | Q02127 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10410756 | 0.90 | PRMT5 (0.52) | PRMT5DHODHMAPTMAPK1TDP1 | |
| SCHEMBL10411924 | 0.83 | PDE9A (0.43) | PRMT5MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL10411402 | 0.81 | FFAR4 (0.42) | PRMT5MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL10411556 | 0.80 | FFAR4 (0.41) | PRMT5MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL10412617 | 0.76 | ABCB1 (0.45) | — | |
| SCHEMBL2530644 | 0.75 | PDE9A (0.49) | MAPK1TDP1HTTSMN1; SMN2 | |
| SCHEMBL10700819 | 0.74 | L3MBTL1 (0.45) | PRMT5MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL10869557 | 0.73 | TNKS (0.50) | — | |
| SCHEMBL10411926 | 0.72 | — | — | |
| SCHEMBL12797474 | 0.72 | MRGPRX4 (0.49) | PRMT5DHODHMAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4925853-A | Antiinflammatory, antiallergens, antiulcer agents | BEECHAM GROUP PLC (GB) | 1990-05-15 | — | — | US | disclosed |
| EP-0178413-A1 | Benzimidazoles | BEECHAM GROUP PLC (GB) | 1986-04-23 | — | — | EP | disclosed |