SCHEMBL104123

SCHEMBL104123

O=C(O)OCc1c[nH]c(=O)[nH]c1=O

nearest known ligand 0.49

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ DPYD Q12882 1/20 0.43
▸ GAA P10253 1/20 0.42
▸ LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2028863 0.84 KDM4E (0.48) GAA
SCHEMBL1546531 0.83 GAA (0.40) DPYDGAA
SCHEMBL17964387 0.81 HCAR2 (0.46) DPYD
SCHEMBL17964386 0.81 HCAR2 (0.46) DPYD
SCHEMBL28636559 0.81 DPYD (0.42) DPYDGAA
SCHEMBL2034296 0.80 DPYD (0.42) DPYDGAA
SCHEMBL30716110 0.79 GAA (0.47) DPYDGAALMNA
SCHEMBL17988578 0.77 KMT2A (0.45) —
SCHEMBL17988571 0.77 KEAP1 (0.37) LMNA
SCHEMBL19996951 0.77 DPYD (0.35) DPYDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 15674 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250368986-A1 ELECTROCHEMICAL SYNTHESIS WITH REDOX STABLE NUCLEOTIDES ATLAS DATA STORAGE INC (US) 2025-12-04 — — US claimed
US-20250257360-A1 OLIGONUCLEOTIDE INTERFERENCE TREATMENTS OF PROSTATE CANCER UNIV OKLAHOMA (US) 2025-08-14 — — US claimed
US-20250066799-A1 UNNATURAL BASE PAIR COMPOSITIONS AND METHODS OF USE THE SCRIPPS RESEARCH INSTITUTE 2025-02-27 — — US claimed
US-12146139-B2 Oligonucleotide interference treatments of prostate cancer THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) 2024-11-19 — — US claimed
US-20230235339-A1 IMPORT OF UNNATURAL OR MODIFIED NUCLEOSIDE TRIPHOSPHATES INTO CELLS VIA NUCLEIC ACID TRIPHOSPHATE TRANSPORTERS THE SCRIPPS RESEARCH INSTITUTE 2023-07-27 — — US claimed
US-20230148152-A1 METHOD OF SYNTHESIZING SINGLE-STRANDED NUCLEOTIDE SEQUENCE, BLOCKED NUCLEOSIDE TRIPHOSPHATES AND RELATED METHODS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2023-05-11 — — US claimed
EP-4058152-A1 OLIGONUCLEOTIDE INTERFERENCE TREATMENTS OF PROSTATE CANCER The Board of Regents of the University of Oklahoma (US) 2022-09-21 — — EP claimed
US-20220275374-A1 OLIGONUCLEOTIDE INTERFERENCE TREATMENTS OF PROSTATE CANCER THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA 2022-09-01 — — US claimed
US-20220243244-A1 COMPOSITIONS AND METHODS FOR IN VIVO SYNTHESIS OF UNNATURAL POLYPEPTIDES NATIONAL INSTITUTES OF HEALTH 2022-08-04 — — US claimed
WO-2021097437-A1 OLIGONUCLEOTIDE INTERFERENCE TREATMENTS OF PROSTATE CANCER THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) 2021-05-20 — — WO claimed
US-20090227489-A1 STAT3 Agonists and Antagonists and Therapeutic Uses Thereof JOHNS HOPKINS UNIVERSITY (US) 2009-09-10 — — US claimed
EP-1308511-A1 Use of angiopoietin-like 1 and angiopoietin-like 2 nucleic acids and proteins for the treatment of blood-related disorders and defects in vasculature. Mermaid Pharmaceuticals GmbH (DE) 2003-05-07 — — EP claimed
EP-1295130-A2 NIMR COMPOSITIONS AND THEIR METHODS OF USE TRUSTEES OF TUFTS COLLEGE (US) 2003-03-26 — — EP claimed
JP-2002531470-A — — 2002-09-24 — — JP claimed
EP-1163374-A2 ARRAYS OF ORGANIC COMPOUNDS ATTACHED TO SURFACES Syntrix Biochip, Inc. (US) 2001-12-19 — — EP claimed
WO-2001070776-A2 NIMR COMPOSITIONS AND THEIR METHODS OF USE TRUSTEES OF TUFTS COLLEGE (US) 2001-09-27 — — WO claimed
WO-2000033084-A2 ARRAYS OF ORGANIC COMPOUNDS ATTACHED TO SURFACES SYNTRIX BIOCHIP, INC. (US) 2000-06-08 — — WO claimed
US-5998596-A Inhibition of protein kinase activity by aptameric action of oligonucleotides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1999-12-07 — — US claimed
WO-1998042723-A9 METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF NEUROPSYCHIATRIC DISORDERS — 1999-03-04 — — WO claimed
US-5486603-A Oligonucleotide having enhanced binding affinity GILEAD SCIENCES, INC. (US) 1996-01-23 — — US claimed
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